The Unusual Suspects—Innate Lymphoid Cells as Novel Therapeutic Targets in IBD|
Innate lymphoid cells (ILCs) rapidly respond to environmental cues, including cytokines, metabolic signals and luminal bacteria. They are potent and immediate producers of key cytokines linked to IBD pathogenesis, including TNF, IL-17, IL-22 and IFN-γ. Some subsets are implicated as mediators of chronic intestinal inflammation, whereas others might provide protective functions. [Nat Rev Gastroenterol Hepatol] Abstract
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